Transforming a Toxic Non-Ionizable Drug into an Efficacious Liposome via Ionizable Prodrug and Remote Loading Strategies against Malignant Breast Tumors.

Zhang, Ximing; Zhao, Fangxue; Feng, Jing; Chen, Cong; He, Zhonggui; Sun, Mengchi; Sun, Jin

Zhang, Ximing; Zhao, Fangxue; Feng, Jing; Chen, Cong; He, Zhonggui; Sun, Mengchi; Sun, Jin.

Afiliação

Zhang X; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning, China.
Zhao F; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning, China.
Feng J; Department of Pharmacy, Dalian Municipal Central Hospital, Dalian 116033, Liaoning, China.
Chen C; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning, China.
He Z; Asia Australia Business College, Liaoning University, Shenyang 110136, Liaoning, China.
Sun M; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning, China.
Sun J; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning, China.

Mol Pharm ; 20(5): 2642-2649, 2023 05 01.

Article em En | MEDLINE | ID: mdl-37043673

Assuntos

Neoplasias da Mama; Pró-Fármacos; Humanos; Feminino; Lipossomos; Linhagem Celular Tumoral; Paclitaxel/uso terapêutico; Neoplasias da Mama/tratamento farmacológico

Palavras-chave

Lipusu; cancer therapy; drug delivery; liposome; paclitaxel

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Pró-Fármacos Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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