Mutation at the Site of Hydroxylation in the Ribosomal Protein uL15 (RPL27a) Causes Specific Changes in the Repertoire of mRNAs Translated in Mammalian Cells.

Zolotenkova, Elizaveta A; Gopanenko, Alexander V; Tupikin, Alexey E; Kabilov, Marsel R; Malygin, Alexey A

Zolotenkova, Elizaveta A; Gopanenko, Alexander V; Tupikin, Alexey E; Kabilov, Marsel R; Malygin, Alexey A.

Afiliação

Zolotenkova EA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Gopanenko AV; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Tupikin AE; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Kabilov MR; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Malygin AA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.

Int J Mol Sci ; 24(7)2023 Mar 24.

Article em En | MEDLINE | ID: mdl-37047141

Assuntos

Biossíntese de Proteínas; Proteínas Ribossômicas; Humanos; Animais; Proteínas Ribossômicas/genética; Proteínas Ribossômicas/metabolismo; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Hidroxilação; Células HEK293; Mutação; Mamíferos/metabolismo

Palavras-chave

HEK293T cells; RNA-seq; RPL27a; differentially expressed genes; polysome profiling; translation; uL15 hydroxylation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Ribossômicas / Biossíntese de Proteínas Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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