The Attenuation of Insulin/IGF-1 Signaling Pathway Plays a Crucial Role in the Myo-Inositol-Alleviated Aging in <i>Caenorhabditis elegans</i>.

Yang, Nae-Cherng; Chin, Chia-Yu; Zheng, Ya-Xin; Lee, Inn

The Attenuation of Insulin/IGF-1 Signaling Pathway Plays a Crucial Role in the Myo-Inositol-Alleviated Aging in Caenorhabditis elegans.

Yang, Nae-Cherng; Chin, Chia-Yu; Zheng, Ya-Xin; Lee, Inn.

Afiliação

Yang NC; Department of Nutrition, Chung Shan Medical University, Taichung 402, Taiwan.
Chin CY; Department of Nutrition, Chung Shan Medical University Hospital, Taichung 402, Taiwan.
Zheng YX; Department of Nutrition, Chung Shan Medical University, Taichung 402, Taiwan.
Lee I; Department of Nutrition, Chung Shan Medical University, Taichung 402, Taiwan.

Int J Mol Sci ; 24(7)2023 Mar 24.

Article em En | MEDLINE | ID: mdl-37047164

Assuntos

Proteínas de Caenorhabditis elegans; Caenorhabditis elegans; Animais; Caenorhabditis elegans/metabolismo; Insulina/metabolismo; Fator de Crescimento Insulin-Like I/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Proteínas de Caenorhabditis elegans/genética; Proteínas de Caenorhabditis elegans/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Envelhecimento; Transdução de Sinais; Insulina Regular Humana/farmacologia; Inositol/farmacologia; Fatores de Transcrição Forkhead/metabolismo

Palavras-chave

C. elegans; PI3K inhibitor; insulin/insulin-like growth factor 1 signaling pathway; longevity; myo-inositol

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Caenorhabditis elegans / Proteínas de Caenorhabditis elegans Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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