Acoustic tweezers using bisymmetric coherent surface acoustic waves for dynamic and reconfigurable manipulation of particle multimers.

HYPOTHESIS: The accurate and dynamic manipulation of multiple micro-sized objects has always been a technical challenge in areas of colloid assembly, tissue engineering, and organ regeneration. The hypothesis of this paper is the precise modulation and parallel manipulation of morphology of individual and multiple colloidal multimers can be achieved by customizing acoustic field. EXPERIMENTS: Herein, we present a colloidal multimer manipulation method by using acoustic tweezers with bisymmetric coherent surface acoustic waves (SAWs), which enables contactless morphology modulation of individual colloidal multimers and patterning arrays by regulating the shape of acoustic field to specific desired distributions with high accuracy. Rapid switching of multimer patterning arrays, morphology modulation of individual multimers, and controllable rotation can be achieved by regulating coherent wave vector configurations and phase relations in real time. FINDINGS: To demonstrate the capabilities of this technology, we have firstly achieved eleven patterns of deterministic morphology switching for single hexamer and precise switching between three array modes. In addition, the assembly of multimers with three kinds of specific widths and controllable rotation of single multimers and arrays were demonstrated from 0 to 22.4 rpm (tetramers). Therefore, this technique enables reversible assembly and dynamic manipulation of particles and/or cells in colloid synthesis applications.