Cell-free fetal DNA impairs trophoblast migration in a TLR9-dependent manner and can be reversed by hydroxychloroquine.

León-Martínez, Daisy; Lynn, Tatyana; Abrahams, Vikki M

León-Martínez, Daisy; Lynn, Tatyana; Abrahams, Vikki M.

Afiliação

León-Martínez D; Department of Obstetrics, Gynecology & Reproductive Sciences, Yale School of Medicine, New Haven, CT, USA.
Lynn T; Department of Obstetrics, Gynecology & Reproductive Sciences, Yale School of Medicine, New Haven, CT, USA.
Abrahams VM; Department of Obstetrics, Gynecology & Reproductive Sciences, Yale School of Medicine, New Haven, CT, USA. Electronic address: vikki.abrahams@yale.edu.

J Reprod Immunol ; 157: 103945, 2023 06.

Article em En | MEDLINE | ID: mdl-37062109

Assuntos

Ácidos Nucleicos Livres; Pré-Eclâmpsia; Gravidez; Feminino; Humanos; Trofoblastos/fisiologia; Placenta; Hidroxicloroquina; Receptor Toll-Like 9; Ácidos Nucleicos Livres/farmacologia; Linhagem Celular; DNA/farmacologia; Aspirina/farmacologia

Palavras-chave

Cell-free fetal DNA; Migration; Placenta; Preeclampsia; TLR9; Trophoblast

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pré-Eclâmpsia / Ácidos Nucleicos Livres Tipo de estudo: Prognostic_studies Limite: Female / Humans / Pregnancy Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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