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Restoration of aberrant gene expression of monocytes in systemic lupus erythematosus via a combined transcriptome-reversal and network-based drug repurposing strategy.
Nikolakis, Dimitrios; Garantziotis, Panagiotis; Sentis, George; Fanouriakis, Antonis; Bertsias, George; Frangou, Eleni; Nikolopoulos, Dionysis; Banos, Aggelos; Boumpas, Dimitrios T.
Afiliação
  • Nikolakis D; Amsterdam Institute for Gastroenterology Endocrinology and Metabolism, Department of Gastroenterology, Amsterdam UMC, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam, 1105 AZ, The Netherlands.
  • Garantziotis P; Department of Rheumatology and Clinical Immunology, Amsterdam Rheumatology & Immunology Center (ARC), Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
  • Sentis G; Amsterdam Institute for Infection & Immunity, Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
  • Fanouriakis A; Onassis Foundation, Athens, Greece.
  • Bertsias G; Laboratory of Autoimmunity and Inflammation, Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.
  • Frangou E; Department Rheumatology and Immunology, Hannover Medical School, Hannover, Germany.
  • Nikolopoulos D; Laboratory of Autoimmunity and Inflammation, Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.
  • Banos A; Rheumatology and Clinical Immunology Unit, Department of Internal Medicine, Attikon University Hospital, Athens, 4th, Greece.
  • Boumpas DT; Department of Propaedeutic Internal Medicine, "Laiko" General Hospital, Athens, Greece.
BMC Genomics ; 24(1): 207, 2023 Apr 18.
Article em En | MEDLINE | ID: mdl-37072752
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Lúpus Eritematoso Sistêmico Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Lúpus Eritematoso Sistêmico Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article