FTO overexpression expedites wound healing and alleviates depression in burn rats through facilitating keratinocyte migration and angiogenesis via mediating TFPI-2 demethylation.

Xu, Zihan; Zhu, Xiumei; Mu, Shengzhi; Fan, Ronghui; Wang, Benfeng; Gao, Wenjie; Kang, Tao

Xu, Zihan; Zhu, Xiumei; Mu, Shengzhi; Fan, Ronghui; Wang, Benfeng; Gao, Wenjie; Kang, Tao.

Afiliação

Xu Z; Department of Burns and Plastic Surgery, Shaanxi Provincial People's Hospital, Xi'an, 710068, China.
Zhu X; Department of Burns and Plastic Surgery, Shaanxi Provincial People's Hospital, Xi'an, 710068, China.
Mu S; Department of Burns and Plastic Surgery, Shaanxi Provincial People's Hospital, Xi'an, 710068, China.
Fan R; Department of Burns and Plastic Surgery, Shaanxi Provincial People's Hospital, Xi'an, 710068, China.
Wang B; Department of Burns and Plastic Surgery, Shaanxi Provincial People's Hospital, Xi'an, 710068, China.
Gao W; Department of Burns and Plastic Surgery, Shaanxi Provincial People's Hospital, Xi'an, 710068, China.
Kang T; Department of Neurology, Shaanxi Provincial People's Hospital, Xi'an, 710068, China. kang201920221209@163.com.

Mol Cell Biochem ; 479(2): 325-335, 2024 Feb.

Article em En | MEDLINE | ID: mdl-37074506

Assuntos

Angiogênese; Queimaduras; Glicoproteínas; Animais; Humanos; Ratos; Dioxigenase FTO Dependente de alfa-Cetoglutarato/genética; Queimaduras/genética; Proliferação de Células; Desmetilação; Depressão/genética; Queratinócitos; Cicatrização

Palavras-chave

Angiogenesis; Burn injury; FTO; Keratinocytes; TFPI-2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Queimaduras / Glicoproteínas / Angiogênese Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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