Genome Analysis of Triploid Hybrid Leishmania Parasite from the Neotropics.

Van den Broeck, Frederik; Heeren, Senne; Maes, Ilse; Sanders, Mandy; Cotton, James A; Cupolillo, Elisa; Alvarez, Eugenia; Garcia, Lineth; Tasia, Maureen; Marneffe, Alice; Dujardin, Jean-Claude; Van der Auwera, Gert

Van den Broeck, Frederik; Heeren, Senne; Maes, Ilse; Sanders, Mandy; Cotton, James A; Cupolillo, Elisa; Alvarez, Eugenia; Garcia, Lineth; Tasia, Maureen; Marneffe, Alice; Dujardin, Jean-Claude; Van der Auwera, Gert.

Emerg Infect Dis ; 29(5): 1076-1078, 2023 05.

Article em En | MEDLINE | ID: mdl-37081624

ABSTRACT

ABSTRACT

We discovered a hybrid Leishmania parasite in Costa Rica that is genetically similar to hybrids from Panama. Genome analyses demonstrated the hybrid is triploid and identified L. braziliensis and L. guyanensis-related strains as parents. Our findings highlight the existence of poorly sampled Leishmania (Viannia) variants infectious to humans.

Assuntos

Leishmania; Leishmaniose Cutânea; Triploidia; Animais; Humanos; Leishmania/genética; Leishmaniose Cutânea/parasitologia; Parasitos; Genômica

Palavras-chave

Belgium; Costa Rica; Leishmania; Panama; cutaneous parasites; genetics; genomics; interspecific hybridization; leishmaniasis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leishmaniose Cutânea / Triploidia / Leishmania Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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