Cucurbitacin IIb Extracted from Hemsleya penxianensis Induces Cell Cycle Arrest and Apoptosis in Bladder Cancer Cells by Regulating Cell Cycle Checkpoints and Mitochondrial Apoptotic Pathway.

Chen, Nan; Li, Peng; Liu, Litao; Zhang, Jun; Cao, Zepeng; Chen, Ziwen; Xu, Xudong; Ma, Guoxu; Huo, Xiaowei

Chen, Nan; Li, Peng; Liu, Litao; Zhang, Jun; Cao, Zepeng; Chen, Ziwen; Xu, Xudong; Ma, Guoxu; Huo, Xiaowei.

Afiliação

Chen N; College of Pharmaceutical Sciences, Key Laboratory of Pharmaceutical Quality Control of Hebei Province, Hebei University, Baoding, 071002, China.
Li P; College of Basic Sciences, Shanxi Agricultural University, Taigu, 030801, China.
Liu L; Department of General Surgery, Affiliated Hospital of Hebei University, Baoding, 071002, China.
Zhang J; College of Pharmaceutical Sciences, Key Laboratory of Pharmaceutical Quality Control of Hebei Province, Hebei University, Baoding, 071002, China.
Cao Z; College of Pharmaceutical Sciences, Key Laboratory of Pharmaceutical Quality Control of Hebei Province, Hebei University, Baoding, 071002, China.
Chen Z; College of Pharmaceutical Sciences, Key Laboratory of Pharmaceutical Quality Control of Hebei Province, Hebei University, Baoding, 071002, China.
Xu X; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China.
Ma G; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China. mgxfl8785@163.com.
Huo X; College of Pharmaceutical Sciences, Key Laboratory of Pharmaceutical Quality Control of Hebei Province, Hebei University, Baoding, 071002, China. huoxiaoweiforever@163.com.

Plant Foods Hum Nutr ; 78(2): 483-492, 2023 Jun.

Article em En | MEDLINE | ID: mdl-37086373

Assuntos

Transdução de Sinais; Neoplasias da Bexiga Urinária; Fosfatidilinositol 3-Quinases/metabolismo; Fosfatidilinositol 3-Quinases/farmacologia; Linhagem Celular Tumoral; Pontos de Checagem do Ciclo Celular; Neoplasias da Bexiga Urinária/tratamento farmacológico; Neoplasias da Bexiga Urinária/patologia; Apoptose; Proliferação de Células

Palavras-chave

Apoptosis; Bladder cancer; Cell cycle; Cucurbitacin IIb; RNA-seq

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / Transdução de Sinais Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google