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NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency.
Sun, Congxin; Seranova, Elena; Cohen, Malkiel A; Chipara, Miruna; Roberts, Jennie; Astuti, Dewi; Palhegyi, Adina M; Acharjee, Animesh; Sedlackova, Lucia; Kataura, Tetsushi; Otten, Elsje G; Panda, Prashanta K; Lara-Reyna, Samuel; Korsgen, Miriam E; Kauffman, Kevin J; Huerta-Uribe, Alejandro; Zatyka, Malgorzata; Silva, Luiz F S E; Torresi, Jorge; Zhang, Shupei; Hughes, Georgina W; Ward, Carl; Kuechler, Erich R; Cartwright, David; Trushin, Sergey; Trushina, Eugenia; Sahay, Gaurav; Buganim, Yosef; Lavery, Gareth G; Gsponer, Joerg; Anderson, Daniel G; Frickel, Eva-Maria; Rosenstock, Tatiana R; Barrett, Timothy; Maddocks, Oliver D K; Tennant, Daniel A; Wang, Haoyi; Jaenisch, Rudolf; Korolchuk, Viktor I; Sarkar, Sovan.
Afiliação
  • Sun C; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Seranova E; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Cohen MA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  • Chipara M; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Roberts J; Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Astuti D; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Palhegyi AM; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Acharjee A; Institute of Cancer and Genomic Sciences, Centre for Computational Biology, University of Birmingham, Birmingham B15 2TT, UK; Institute of Translational Medicine, University Hospitals Birmingham, NHS Foundation Trust, Birmingham B15 2TT, UK; NIHR Surgical Reconstruction and Microbiology Research Cen
  • Sedlackova L; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE4 5PL, UK.
  • Kataura T; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE4 5PL, UK.
  • Otten EG; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE4 5PL, UK.
  • Panda PK; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Lara-Reyna S; Institute of Microbiology and Infection, University of Birmingham, Birmingham B15 2TT, UK.
  • Korsgen ME; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Kauffman KJ; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  • Huerta-Uribe A; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.
  • Zatyka M; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Silva LFSE; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Torresi J; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Zhang S; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  • Hughes GW; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Ward C; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Kuechler ER; Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
  • Cartwright D; Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Trushin S; Department of Neurology, Mayo Clinic, Rochester, MN 55901, USA.
  • Trushina E; Department of Neurology, Mayo Clinic, Rochester, MN 55901, USA.
  • Sahay G; Department of Pharmaceutical Sciences and Department of Biomedical Engineering, College of Pharmacy, Oregon State University, Portland, OR 97201, USA.
  • Buganim Y; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.
  • Lavery GG; Department for Biosciences, Nottingham Trent University, Nottingham NG11 8NS, UK.
  • Gsponer J; Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
  • Anderson DG; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Institute for Medical Engineering and Science, Massachusetts Institute of Tec
  • Frickel EM; Institute of Microbiology and Infection, University of Birmingham, Birmingham B15 2TT, UK.
  • Rosenstock TR; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Barrett T; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK; Department of Endocrinology, Birmingham Women's and Children's Hospital, Steelehouse Lane, Birmingham B4 6NH, UK.
  • Maddocks ODK; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.
  • Tennant DA; Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Wang H; The State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Chaoyang District, Beijing 100101, China.
  • Jaenisch R; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  • Korolchuk VI; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE4 5PL, UK. Electronic address: viktor.korolchuk@newcastle.ac.uk.
  • Sarkar S; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK. Electronic address: s.sarkar@bham.ac.uk.
Cell Rep ; 42(5): 112372, 2023 05 30.
Article em En | MEDLINE | ID: mdl-37086404
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: NAD / Mononucleotídeo de Nicotinamida Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: NAD / Mononucleotídeo de Nicotinamida Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article