Live-cell imaging identifies cAMP microdomains regulating ß-adrenoceptor-subtype-specific lipolytic responses in human white adipocytes.

De Jong, Kirstie A; Ehret, Sandra; Heeren, Joerg; Nikolaev, Viacheslav O

De Jong, Kirstie A; Ehret, Sandra; Heeren, Joerg; Nikolaev, Viacheslav O.

Afiliação

De Jong KA; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ehret S; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Heeren J; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Nikolaev VO; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: v.nikolaev@uke.de.

Cell Rep ; 42(5): 112433, 2023 05 30.

Article em En | MEDLINE | ID: mdl-37099421

Assuntos

Diabetes Mellitus Tipo 2; Lipólise; Humanos; Lipólise/fisiologia; Adipócitos Brancos/metabolismo; AMP Cíclico/metabolismo; Receptores Adrenérgicos beta/metabolismo

Palavras-chave

3',5'-cyclic adenosine monophosphate; CP: Metabolism; diabetes; fluorescence resonance energy transfer; phosphodiesterases; white adipocytes; ß-adrenergic receptor;

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Lipólise Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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