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High-Dose Spermidine Supplementation Does Not Increase Spermidine Levels in Blood Plasma and Saliva of Healthy Adults: A Randomized Placebo-Controlled Pharmacokinetic and Metabolomic Study.
Senekowitsch, Stefan; Wietkamp, Eliza; Grimm, Michael; Schmelter, Franziska; Schick, Philipp; Kordowski, Anna; Sina, Christian; Otzen, Hans; Weitschies, Werner; Smollich, Martin.
Afiliação
  • Senekowitsch S; Department of Biopharmaceutics and Pharmaceutical Technology, University of Greifswald, 17489 Greifswald, Germany.
  • Wietkamp E; Institute of Nutritional Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, University of Lübeck, 23538 Lübeck, Germany.
  • Grimm M; Department of Biopharmaceutics and Pharmaceutical Technology, University of Greifswald, 17489 Greifswald, Germany.
  • Schmelter F; Institute of Nutritional Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, University of Lübeck, 23538 Lübeck, Germany.
  • Schick P; Department of Biopharmaceutics and Pharmaceutical Technology, University of Greifswald, 17489 Greifswald, Germany.
  • Kordowski A; Institute of Nutritional Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, University of Lübeck, 23538 Lübeck, Germany.
  • Sina C; Institute of Nutritional Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, University of Lübeck, 23538 Lübeck, Germany.
  • Otzen H; Institute of Nutritional Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, University of Lübeck, 23538 Lübeck, Germany.
  • Weitschies W; Department of Biopharmaceutics and Pharmaceutical Technology, University of Greifswald, 17489 Greifswald, Germany.
  • Smollich M; Institute of Nutritional Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, University of Lübeck, 23538 Lübeck, Germany.
Nutrients ; 15(8)2023 Apr 12.
Article em En | MEDLINE | ID: mdl-37111071
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espermidina / Espermina Tipo de estudo: Clinical_trials Limite: Adult / Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espermidina / Espermina Tipo de estudo: Clinical_trials Limite: Adult / Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article