Effects of intrathecally administered interferon &#945; on chronic constriction injury model rats' mechanical pain threshold and G protein expression in the spinal cord.

Guo, Yaoyao; Xue, Zhaoxia; Yang, Baozhong; Liu, Liwei; Zhang, Peng; Shi, Jin; Fu, Xiurong; Xue, Yanming; Hao, Yanfei; Ji, Gaoliang

Effects of intrathecally administered interferon α on chronic constriction injury model rats' mechanical pain threshold and G protein expression in the spinal cord.

Guo, Yaoyao; Xue, Zhaoxia; Yang, Baozhong; Liu, Liwei; Zhang, Peng; Shi, Jin; Fu, Xiurong; Xue, Yanming; Hao, Yanfei; Ji, Gaoliang.

Afiliação

Guo Y; Department of Anesthesiology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, China.
Xue Z; Department of Pain, the First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Yang B; Department of Anesthesiology, the First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Liu L; Department of Pain, the First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Zhang P; Department of Anesthesiology, the Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Shi J; Department of Anesthesiology, Datong Third People's Hospital, Datong, Shanxi, China.
Fu X; Department of Anesthesiology, the First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Xue Y; Department of Anesthesiology, Yantaishan Hospital, Yantai, Shandong, China.
Hao Y; Department of Anesthesiology, Jincheng Grand Hospital, Jincheng, Shanxi, China.
Ji G; Department of Anesthesiology, Jincheng Grand Hospital, Jincheng, Shanxi, China.

Folia Neuropathol ; 61(1): 97-104, 2023.

Article em En | MEDLINE | ID: mdl-37114965

Assuntos

Interferon-alfa; Limiar da Dor; Ratos; Animais; Ratos Sprague-Dawley; Interferon-alfa/farmacologia; Interferon-alfa/metabolismo; Constrição; Solução Salina/metabolismo; Solução Salina/farmacologia; Proteínas de Ligação ao GTP/metabolismo; Proteínas de Ligação ao GTP/farmacologia; RNA Mensageiro/metabolismo; Medula Espinal/metabolismo; Derivados da Morfina/metabolismo; Derivados da Morfina/farmacologia

Palavras-chave

CCI model; G protein; analgesia; intrathecal administration; rats; interferon a

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interferon-alfa / Limiar da Dor Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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