STING controls opioid-induced itch and chronic itch via spinal tank-binding kinase 1-dependent type I interferon response in mice.

Li, Nan; Wang, Chunyan; Zhao, Yuying; Wang, Yigang; Gao, Tianyu; Yu, Yonghao; Wang, Guolin; Zhang, Linlin

Li, Nan; Wang, Chunyan; Zhao, Yuying; Wang, Yigang; Gao, Tianyu; Yu, Yonghao; Wang, Guolin; Zhang, Linlin.

Afiliação

Li N; Department of Anesthesiology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Wang C; Tianjin Research Institute of Anesthesiology, Tianjin, 300052, China.
Zhao Y; Department of Anesthesiology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Wang Y; Tianjin Research Institute of Anesthesiology, Tianjin, 300052, China.
Gao T; Department of Anesthesiology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Yu Y; Tianjin Research Institute of Anesthesiology, Tianjin, 300052, China.
Wang G; Department of Anesthesiology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Zhang L; Tianjin Research Institute of Anesthesiology, Tianjin, 300052, China.

J Neuroinflammation ; 20(1): 101, 2023 Apr 30.

Article em En | MEDLINE | ID: mdl-37122031

Assuntos

Dermatite de Contato; Dermatite; Interferon Tipo I; Animais; Camundongos; Analgésicos Opioides/farmacologia; Fator Regulador 3 de Interferon/metabolismo; Interferon Tipo I/metabolismo; Morfina; Dor; Prurido/induzido quimicamente; Prurido/tratamento farmacológico; Sufentanil/efeitos adversos

Palavras-chave

Chronic itch; Opioid-induced itch; STING; TBK1; Type I interferon

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interferon Tipo I / Dermatite / Dermatite de Contato Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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