Fluorogenic substrates and pre-column derivatization for monitoring the activity of bile salt hydrolase from Clostridium perfringens.

Keuler, Tim; Wolf, Valentina; Lemke, Carina; Voget, Rabea; Braune, Annett; Gütschow, Michael

Keuler, Tim; Wolf, Valentina; Lemke, Carina; Voget, Rabea; Braune, Annett; Gütschow, Michael.

Afiliação

Keuler T; Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany.
Wolf V; Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany.
Lemke C; Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany.
Voget R; Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany.
Braune A; Research Group Intestinal Microbiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Arthur-Scheunert-Allee 114-116, D-14558 Nuthetal, Germany. Electronic address: braune@dife.de.
Gütschow M; Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany. Electronic address: guetschow@uni-bonn.de.

Bioorg Chem ; 138: 106574, 2023 09.

Article em En | MEDLINE | ID: mdl-37163789

Assuntos

Clostridium perfringens; Corantes Fluorescentes; Humanos; Amidoidrolases/metabolismo; Bactérias/metabolismo; Ácidos e Sais Biliares

Palavras-chave

7-Nitrobenzo[c][1,2,5]oxadiazole; Bile salt hydrolase; Fluorogenic substrates; Precolumn derivatization; Taurocholic acid

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Clostridium perfringens / Corantes Fluorescentes Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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