[Subclinical markers of liver damage in patients with arterial hypertension and obesity].
Ter Arkh
; 94(12): 1367-1373, 2023 Jan 16.
Article
em Ru
| MEDLINE
| ID: mdl-37167180
ABSTRACT
AIM:
To investigate the possibility of preclinical detection of liver damage in patients with hypertension and obesity. MATERIALS ANDMETHODS:
The study included 168 patients with hypertension aged 30 to 60 years. All patients underwent general clinical and laboratory-instrumental examination, including ultrasound of the abdominal organs with Doppler assessment of blood flow and determination of markers such as ALT, AST, TG, lipid profile indicators at inclusion, after a month, three months and nine months.RESULTS:
Depending on the presence of obesity, all patients with hypertension were divided into two groups. Obese patients had a statistically significant increase in office blood pressure, FSI, the ratio of TG and LDL-C to HDL-C, a more significant higher average levels of glucose, TG and ALT levels, as well as impaired hepatic blood flow according to ultrasound.CONCLUSION:
Indicators of FSI, ALT/AST ratio, ratio of TG and LDL-С to HDL-C as well as assessment of hepatic blood flow indicators can be used for early diagnosis of nonalcoholic fatty liver disease, as they predict liver steatosis.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hepatopatia Gordurosa não Alcoólica
/
Hipertensão
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
/
Screening_studies
Limite:
Humans
Idioma:
Ru
Ano de publicação:
2023
Tipo de documento:
Article