High tumor burden in patients with non-small-cell lung cancer: a Delphi survey among Spanish oncologists.
Future Oncol
; 19(14): 991-1002, 2023 May.
Article
em En
| MEDLINE
| ID: mdl-37170838
ABSTRACT
Aim:
To define high tumor burden (HTB) in non-small-cell lung cancer.Methods:
A total of five oncologists initiated the project, selecting 66 participants, and elaborated a questionnaire with 26 statements using the Delphi method with a 9-point Likert scale of agreement.Results:
Factors with moderate strength of consensus were identified, including a sum of the longest diameter of lesions ≥10 cm, elevated Lactate dehydrogenase, hepatic involvement, lymphangitis carcinomatosis, brain involvement unapproachable with local techniques and pericardial effusion. There was a consensus against increases in tumor markers and asymptomatic brain involvement being related to HTB. HTB was considered a relevant factor for treatment selection supporting the choice of combination regimens versus immunotherapy only.Conclusion:
In this Delphi study, experts defined several factors associated with HTB in non-small cell lung cancer.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Carcinoma Pulmonar de Células não Pequenas
/
Oncologistas
/
Neoplasias Pulmonares
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article