Efficacy and safety of dupilumab in patients with severe chronic hand eczema with inadequate response or intolerance to alitretinoin: a randomized, double-blind, placebo-controlled phase IIb proof-of-concept study.

Voorberg, Angelique N; Kamphuis, Esmé; Christoffers, Wietske A; Schuttelaar, Marie L A

Efficacy and safety of dupilumab in patients with severe chronic hand eczema with inadequate response or intolerance to alitretinoin: a randomized, double-blind, placebo-controlled phase IIb proof-of-concept study.

Voorberg, Angelique N; Kamphuis, Esmé; Christoffers, Wietske A; Schuttelaar, Marie L A.

Afiliação

Voorberg AN; Department of Dermatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Kamphuis E; Department of Dermatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Christoffers WA; Department of Dermatology, Isala Dermatologic Center, Zwolle, the Netherlands.
Schuttelaar MLA; Department of Dermatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

Br J Dermatol ; 189(4): 400-409, 2023 09 15.

Article em En | MEDLINE | ID: mdl-37170922

Assuntos

Dermatite Atópica; Eczema; Adulto; Humanos; Alitretinoína/efeitos adversos; Anticorpos Monoclonais Humanizados; Eczema/tratamento farmacológico; Eczema/induzido quimicamente; Dermatite Atópica/tratamento farmacológico; Resultado do Tratamento; Método Duplo-Cego; Índice de Gravidade de Doença

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dermatite Atópica / Eczema Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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