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A continuum mechanical porous media model for vertebroplasty: Numerical simulations and experimental validation.
Trivedi, Zubin; Gehweiler, Dominic; Wychowaniec, Jacek K; Ricken, Tim; Gueorguiev, Boyko; Wagner, Arndt; Röhrle, Oliver.
Afiliação
  • Trivedi Z; Institute for Modelling and Simulation of Biomechanical Systems, University of Stuttgart, Pfaffenwaldring 5a, 70569, Stuttgart, Germany. zubin.trivedi@imsb.uni-stuttgart.de.
  • Gehweiler D; AO Research Institute (ARI), Clavadelerstrasse 8, 7270, Davos, Switzerland.
  • Wychowaniec JK; AO Research Institute (ARI), Clavadelerstrasse 8, 7270, Davos, Switzerland.
  • Ricken T; Institute of Structural Mechanics and Dynamics in Aerospace Engineering, University of Stuttgart, Pfaffenwaldring 27, 70569, Stuttgart, Germany.
  • Gueorguiev B; AO Research Institute (ARI), Clavadelerstrasse 8, 7270, Davos, Switzerland.
  • Wagner A; Institute of Applied Mechanics (CE), University of Stuttgart, Pfaffenwaldring 7, 70569, Stuttgart, Germany.
  • Röhrle O; Stuttgart Center for Simulation Science (SC SimTech), University of Stuttgart, Pfaffenwaldring 5a, 70569, Stuttgart, Germany.
Biomech Model Mechanobiol ; 22(4): 1253-1266, 2023 Aug.
Article em En | MEDLINE | ID: mdl-37171687
The outcome of vertebroplasty is hard to predict due to its dependence on complex factors like bone cement and marrow rheologies. Cement leakage could occur if the procedure is done incorrectly, potentially causing adverse complications. A reliable simulation could predict the patient-specific outcome preoperatively and avoid the risk of cement leakage. Therefore, the aim of this work was to introduce a computationally feasible and experimentally validated model for simulating vertebroplasty. The developed model is a multiphase continuum-mechanical macro-scale model based on the Theory of Porous Media. The related governing equations were discretized using a combined finite element-finite volume approach by the so-called Box discretization. Three different rheological upscaling methods were used to compare and determine the most suitable approach for this application. For validation, a benchmark experiment was set up and simulated using the model. The influence of bone marrow and parameters like permeability, porosity, etc., was investigated to study the effect of varying conditions on vertebroplasty. The presented model could realistically simulate the injection of bone cement in porous materials when used with the correct rheological upscaling models, of which the semi-analytical averaging of the viscosity gave the best results. The marrow viscosity is identified as the crucial reference to categorize bone cements as 'high- 'or 'low-' viscosity in the context of vertebroplasty. It is confirmed that a cement with higher viscosity than the marrow ensures stable development of the injection and a proper cement interdigitation inside the vertebra.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cimentos Ósseos / Vertebroplastia Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cimentos Ósseos / Vertebroplastia Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article