Analysis of the potential biological mechanisms of diosmin against renal fibrosis based on network pharmacology and molecular docking approach.

Zhao, Wen-Man; Wang, Zhi-Juan; Shi, Rui; Zhu, Yuyu; Li, Xun-Liang; Wang, De-Guang

Zhao, Wen-Man; Wang, Zhi-Juan; Shi, Rui; Zhu, Yuyu; Li, Xun-Liang; Wang, De-Guang.

Afiliação

Zhao WM; Department of Nephrology, the Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Wang ZJ; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, the Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Shi R; Department of Nephrology, the Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Zhu Y; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, the Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Li XL; Department of Nephrology, the Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Wang DG; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, the Second Affiliated Hospital of Anhui Medical University, Hefei, China.

BMC Complement Med Ther ; 23(1): 157, 2023 May 13.

Article em En | MEDLINE | ID: mdl-37179298

Assuntos

Diosmina; Nefropatias; Humanos; Simulação de Acoplamento Molecular; Metaloproteinase 9 da Matriz; Caspase 3; Diosmina/farmacologia; Farmacologia em Rede; Fosfatidilinositol 3-Quinases; Fibrose

Palavras-chave

Diosmin; Molecular docking; Pharmacological mechanisms; Renal fibrosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diosmina / Nefropatias Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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