A comprehensive analysis of coagulopathy during anti-B cell maturation antigen chimeric antigen receptor-T therapy in multiple myeloma, a retrospective study based on LEGEND-2.

Liu, Rui; Lv, Yang; Hong, Fei; Zhao, Wanhong; Lei, Bo; Liu, Jie; Zhang, Wanggang; He, Aili; Wang, Fangxia

Liu, Rui; Lv, Yang; Hong, Fei; Zhao, Wanhong; Lei, Bo; Liu, Jie; Zhang, Wanggang; He, Aili; Wang, Fangxia.

Afiliação

Liu R; Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Lv Y; Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Hong F; Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Zhao W; Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Lei B; Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Liu J; Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Zhang W; Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
He A; Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Wang F; National-Local Joint Engineering Research Center of Bio Diagnostics and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.

Hematol Oncol ; 41(4): 704-717, 2023 Oct.

Article em En | MEDLINE | ID: mdl-37186314

Assuntos

Transtornos da Coagulação Sanguínea; Mieloma Múltiplo; Receptores de Antígenos Quiméricos; Humanos; Receptores de Antígenos Quiméricos/uso terapêutico; Mieloma Múltiplo/complicações; Mieloma Múltiplo/terapia; Estudos Retrospectivos; Antígeno de Maturação de Linfócitos B/uso terapêutico; Transtornos da Coagulação Sanguínea/terapia; Transtornos da Coagulação Sanguínea/complicações; Síndrome da Liberação de Citocina/etiologia

Palavras-chave

chimeric antigen receptor T cell; coagulopathy; cytokine release syndrome; disseminated intravascular coagulation; liver function; multiple myeloma

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos da Coagulação Sanguínea / Receptores de Antígenos Quiméricos / Mieloma Múltiplo Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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