Temocillin Resistance in the Enterobacter cloacae Complex Is Conferred by a Single Point Mutation in BaeS, Leading to Overexpression of the AcrD Efflux Pump.

Guérin, François; Gravey, François; Reissier, Sophie; Penven, Malo; Michaux, Charlotte; Le Hello, Simon; Cattoir, Vincent

Guérin, François; Gravey, François; Reissier, Sophie; Penven, Malo; Michaux, Charlotte; Le Hello, Simon; Cattoir, Vincent.

Afiliação

Guérin F; Department of Clinical Microbiology, Rennes University Hospital, Rennes, France.
Gravey F; University of Rennes, INSERM UMR 1230 BRM, Rennes, France.
Reissier S; Normandie Université, UNICAEN, UNIROUEN, INSERM UMR 1311 DYNAMICURE, Caen, France.
Penven M; Microbiology Department, CHU Caen, Caen, France.
Michaux C; Department of Clinical Microbiology, Rennes University Hospital, Rennes, France.
Le Hello S; University of Rennes, INSERM UMR 1230 BRM, Rennes, France.
Cattoir V; Department of Clinical Microbiology, Rennes University Hospital, Rennes, France.

Antimicrob Agents Chemother ; 67(6): e0035823, 2023 06 15.

Article em En | MEDLINE | ID: mdl-37195180

Assuntos

Antibacterianos; Proteínas de Membrana Transportadoras; Proteínas de Membrana Transportadoras/genética; Antibacterianos/farmacologia; Antibacterianos/metabolismo; Enterobacter cloacae/genética; Enterobacter cloacae/metabolismo; Escherichia coli/genética; Mutação Puntual; Testes de Sensibilidade Microbiana

Palavras-chave

AcrD; BaeSR; E. asburiae; ECC; MdtABCD

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Antibacterianos Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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