Divergent Synthesis of 1,1-Carbonyl Amino Alkyl Borons from Indoles.
Org Lett
; 25(22): 4038-4043, 2023 Jun 09.
Article
em En
| MEDLINE
| ID: mdl-37229694
ABSTRACT
α-Boryl carbonyl species and α-boryl amino compounds are valuable and important frameworks in organic synthesis. However, the strategies that could merge the two scaffolds into one compound, named 1,1-carbonyl amino alkyl boron, are elusive and underdeveloped. Herein, we present an efficient method that could address this gap and produce 1,1-carbonyl amino alkyl borons from readily accessible indoles via oxidation by m-CPBA or oxone. This reaction features operational simplicity, divergent synthesis, broad substrate scope, and valuable products.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Indóis
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article