Characterization of Stimulatory Action on Voltage-Gated Na<sup>+</sup> Currents Caused by Omecamtiv Mecarbil, Known to Be a Myosin Activator.

Ting, Chih-Yu; Shih, Chia-Lung; Yu, Meng-Cheng; Wu, Chao-Liang; Wu, Sheng-Nan

Characterization of Stimulatory Action on Voltage-Gated Na⁺ Currents Caused by Omecamtiv Mecarbil, Known to Be a Myosin Activator.

Ting, Chih-Yu; Shih, Chia-Lung; Yu, Meng-Cheng; Wu, Chao-Liang; Wu, Sheng-Nan.

Afiliação

Ting CY; Department of Emergency Medicine, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi City 60002, Taiwan.
Shih CL; Clinical Research Center, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi City 60002, Taiwan.
Yu MC; Department of Physiology, National Cheng Kung University Medical College, Tainan 70101, Taiwan.
Wu CL; Clinical Research Center, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi City 60002, Taiwan.
Wu SN; Department of Physiology, National Cheng Kung University Medical College, Tainan 70101, Taiwan.

Biomedicines ; 11(5)2023 May 03.

Article em En | MEDLINE | ID: mdl-37239022

Palavras-chave

cumulative inactivation; late Na+ current; myosin activator; omecamtiv mecarbil; slow inactivation; transient Na+ current; voltage-gated Na+ current; window Na+ current

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article