Pirfenidone Inhibits Alveolar Bone Loss in Ligature-Induced Periodontitis by Suppressing the NF-&#954;B Signaling Pathway in Mice.

Zhang, Zijiao; Song, Juhan; Kwon, Seung-Hee; Wang, Zhao; Park, Suk-Gyun; Piao, Xianyu; Ryu, Je-Hwang; Kim, Nacksung; Kim, Ok-Su; Kim, Sun-Hun; Koh, Jeong-Tae

Pirfenidone Inhibits Alveolar Bone Loss in Ligature-Induced Periodontitis by Suppressing the NF-κB Signaling Pathway in Mice.

Zhang, Zijiao; Song, Juhan; Kwon, Seung-Hee; Wang, Zhao; Park, Suk-Gyun; Piao, Xianyu; Ryu, Je-Hwang; Kim, Nacksung; Kim, Ok-Su; Kim, Sun-Hun; Koh, Jeong-Tae.

Afiliação

Zhang Z; Department of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju 61186, Republic of Korea.
Song J; Hard-Tissue Biointerface Research Center, School of Dentistry, Chonnam National University, Gwangju 61186, Republic of Korea.
Kwon SH; Department of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju 61186, Republic of Korea.
Wang Z; Hard-Tissue Biointerface Research Center, School of Dentistry, Chonnam National University, Gwangju 61186, Republic of Korea.
Park SG; Department of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju 61186, Republic of Korea.
Piao X; Hard-Tissue Biointerface Research Center, School of Dentistry, Chonnam National University, Gwangju 61186, Republic of Korea.
Ryu JH; Department of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju 61186, Republic of Korea.
Kim N; Hard-Tissue Biointerface Research Center, School of Dentistry, Chonnam National University, Gwangju 61186, Republic of Korea.
Kim OS; Department of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju 61186, Republic of Korea.
Kim SH; Hard-Tissue Biointerface Research Center, School of Dentistry, Chonnam National University, Gwangju 61186, Republic of Korea.
Koh JT; Department of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju 61186, Republic of Korea.

Int J Mol Sci ; 24(10)2023 May 12.

Article em En | MEDLINE | ID: mdl-37240020

Assuntos

Perda do Osso Alveolar; Periodontite; Camundongos; Animais; NF-kappa B/metabolismo; Perda do Osso Alveolar/tratamento farmacológico; Perda do Osso Alveolar/etiologia; Perda do Osso Alveolar/metabolismo; Microtomografia por Raio-X; Lipopolissacarídeos/farmacologia; Transdução de Sinais; Osteoclastos/metabolismo; Periodontite/tratamento farmacológico; Periodontite/etiologia; Periodontite/metabolismo; Citocinas/metabolismo; Ligante RANK/metabolismo

Palavras-chave

NF-κB pathway; alveolar bone loss; inflammation; osteoclast differentiation; periodontitis; pirfenidone

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Periodontite / Perda do Osso Alveolar Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google