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Hybrid imaging of prompt x-rays and induced positrons using a pinhole gamma camera during and after irradiation of protons.
Yamamoto, Seiichi; Watabe, Hiroshi; Nakanishi, Kohei; Yabe, Takuya; Yamaguchi, Mitsutaka; Kawachi, Naoki; Kamada, Kei; Yoshikawa, Akira; Islam, Md Rafiqul; Miyake, Masayasu; Tanaka, Kazuo S; Kataoka, Jun.
Afiliação
  • Yamamoto S; Faculty of Science and Engineering, Waseda University, Japan.
  • Watabe H; Cyclotron Radioisotope Center, Tohoku University, Japan.
  • Nakanishi K; Department of Integrated Health Science, Nagoya University, Graduate School of Medicine, Japan.
  • Yabe T; Takasaki Institute of Advanced Quantum Science, Foundational Quantum Technology Research Directorate, National Institutes for Quantum Science and Technology (QST), Japan.
  • Yamaguchi M; Takasaki Institute of Advanced Quantum Science, Foundational Quantum Technology Research Directorate, National Institutes for Quantum Science and Technology (QST), Japan.
  • Kawachi N; Takasaki Institute of Advanced Quantum Science, Foundational Quantum Technology Research Directorate, National Institutes for Quantum Science and Technology (QST), Japan.
  • Kamada K; New Industry Creation Hatchery Center (NICHe), Tohoku University, Japan.
  • Yoshikawa A; New Industry Creation Hatchery Center (NICHe), Tohoku University, Japan.
  • Islam MR; Cyclotron Radioisotope Center, Tohoku University, Japan.
  • Miyake M; Cyclotron Radioisotope Center, Tohoku University, Japan.
  • Tanaka KS; Faculty of Science and Engineering, Waseda University, Japan.
  • Kataoka J; Faculty of Science and Engineering, Waseda University, Japan.
Phys Med Biol ; 68(11)2023 05 30.
Article em En | MEDLINE | ID: mdl-37252715
Objective. Prompt x-ray imaging using a low-energy x-ray camera is a promising method for observing a proton beam's shape from outside the subject. Furthermore, imaging of positrons produced by nuclear reactions with protons is a possible method for observing the beam shape. However, it has not been possible to measure these two types of images with a single imaging system due to the limited imaging capability of existing systems. Imaging of both prompt x-rays and the distribution of positrons may compensate for the shortcomings of each method.Approach. We conducted imaging of the prompt x-ray using a pinhole x-ray camera during irradiation with protons in list mode. Then, after irradiation with protons, imaging of annihilation radiations from the produced positrons was conducted using the same pinhole x-ray camera in list mode. After this imaging, list-mode data were sorted to obtain prompt x-ray images and positron images.Main results. With the proposed procedure, we could measure both prompt x-ray images and induced positron images with a single irradiation by a proton beam. From the prompt x-ray images, ranges and widths of the proton beams could be estimated. The distributions of positrons were slightly wider than those of the prompt x-rays. From the time sequential positron images, we could derive the time activity curves of the produced positrons.Significance. Hybrid imaging of prompt x-rays and induced positrons using a pinhole x-ray camera was achieved. The proposed procedure would be useful for measuring prompt x-ray images during irradiation to estimate the beam structures as well as for measuring the induced positron images after irradiation to estimate the distributions and time activity curves of the induced positrons.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prótons / Terapia com Prótons Tipo de estudo: Health_economic_evaluation Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prótons / Terapia com Prótons Tipo de estudo: Health_economic_evaluation Idioma: En Ano de publicação: 2023 Tipo de documento: Article