Severe hypocalcemia after denosumab administration in a patient with chronic kidney disease: a case report.
J Musculoskelet Neuronal Interact
; 23(2): 285-289, 2023 06 01.
Article
em En
| MEDLINE
| ID: mdl-37259667
ABSTRACT
Patients with altered kidney function are at increased risk of hypocalcemia after denosumab administration. There is however a small number of studies and case reports describing hypocalcemia refractory to treatment. We describe a case of severe hypocalcemia, after the administration of three doses of denosumab, in a young patient with lupus nephritis under corticosteroid coverage and osteopenia. However, more studies are needed in order to extract a safe conclusion about the factors that contribute to the development of severe hypocalcemia in this group of patients.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Osteoporose
/
Insuficiência Renal Crônica
/
Conservadores da Densidade Óssea
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Hipocalcemia
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article