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Natural deletion of mouse carboxylesterases Ces1c/d/e impacts drug metabolism and metabolic syndrome development.
Gan, Changpei; Wang, Jing; Wang, Yaogeng; Martínez-Chávez, Alejandra; Hillebrand, Michel; de Vries, Niels; Beukers, Joke; Lebre, Maria C; Wagenaar, Els; Rosing, Hilde; Klarenbeek, Sjoerd; Bleijerveld, Onno B; Song, Ji-Ying; Altelaar, Maarten; Beijnen, Jos H; Schinkel, Alfred H.
Afiliação
  • Gan C; Division of Pharmacology, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands.
  • Wang J; Division of Pharmacology, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands.
  • Wang Y; Division of Pharmacology, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands.
  • Martínez-Chávez A; Division of Pharmacology, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands.
  • Hillebrand M; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands.
  • de Vries N; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands.
  • Beukers J; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands.
  • Lebre MC; Division of Pharmacology, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands.
  • Wagenaar E; Division of Pharmacology, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands.
  • Rosing H; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands.
  • Klarenbeek S; Experimental Animal Pathology Facility, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands.
  • Bleijerveld OB; Proteomics Core Facility, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands.
  • Song JY; Experimental Animal Pathology Facility, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands.
  • Altelaar M; Proteomics Core Facility, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, and Netherlands Proteomics Center, Paduala
  • Beijnen JH; Division of Pharmacology, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceu
  • Schinkel AH; Division of Pharmacology, The Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands. Electronic address: a.schinkel@nki.nl.
Biomed Pharmacother ; 164: 114956, 2023 Aug.
Article em En | MEDLINE | ID: mdl-37267638

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Hidrolases de Éster Carboxílico / Síndrome Metabólica Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Hidrolases de Éster Carboxílico / Síndrome Metabólica Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article