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Disulfiram combined with chemoimmunotherapy potentiates pancreatic cancer treatment efficacy through the activation of cGAS-STING signaling pathway via suppressing PARP1 expression.
Huang, Shenan; Xie, Peiyi; Huang, Xiaomei; Chen, Zhimeng; Yang, Jinhuan; Wang, Jian; Liu, Cong; Li, Hui; Zhou, Binghai.
Afiliação
  • Huang S; Department of Gastroenterology, The Second Affiliated Hospital of Nanchang University Nanchang 330006, Jiangxi, P. R. China.
  • Xie P; Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University Shanghai 200032, P. R. China.
  • Huang X; Department of Gastroenterology, The Second Affiliated Hospital of Nanchang University Nanchang 330006, Jiangxi, P. R. China.
  • Chen Z; Hepato-Biliary-Pancreatic Surgery Division, Department of General Surgery, The Second Affiliated Hospital of Nanchang University Nanchang 330006, Jiangxi, P. R. China.
  • Yang J; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University Wenzhou 325035, Zhejiang, P. R. China.
  • Wang J; Department of Hepato-Biliary-Pancreatic Surgery, Pingxiang People's Hospital Pingxiang 337099, Jiangxi, P. R. China.
  • Liu C; Hepato-Biliary-Pancreatic Surgery Division, Department of General Surgery, The Second Affiliated Hospital of Nanchang University Nanchang 330006, Jiangxi, P. R. China.
  • Li H; Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education Shanghai 200032, P. R. China.
  • Zhou B; Shanghai Medical College and Zhongshan Hospital Immunotherapy Translational Research Center Shanghai 200031, P. R. China.
Am J Cancer Res ; 13(5): 2055-2065, 2023.
Article em En | MEDLINE | ID: mdl-37293156

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article