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Characterization of the Pharmacokinetic and Pharmacodynamic Profile of Apraglutide, a Glucagon-Like Peptide-2 Analog, in Healthy Volunteers.
Bolognani, Federico; Kruithof, Annelieke C; Schulthess, Pascal; Machacek, Matthias; de Kam, Marieke L; Bergmann, Kirsten R; van Gent, Max; Moerland, Matthijs; Crenn, Pascal; Greig, Gérard; Gal, Pim.
Afiliação
  • Bolognani F; VectivBio AG, Basel, Switzerland (F.B.); Centre for Human Drug Research, Leiden, Netherlands (A.C.K., M.L.d.K., K.R.B., M.v.G., M.Mo., P.G.); LYO-X AG, Basel, Switzerland (P.S., M.Ma.); Leiden University Medical Center, Leiden, Netherlands (A.C.K., M.Mo., P.G.); University Paris-Saclay/APHP, Hospita
  • Kruithof AC; VectivBio AG, Basel, Switzerland (F.B.); Centre for Human Drug Research, Leiden, Netherlands (A.C.K., M.L.d.K., K.R.B., M.v.G., M.Mo., P.G.); LYO-X AG, Basel, Switzerland (P.S., M.Ma.); Leiden University Medical Center, Leiden, Netherlands (A.C.K., M.Mo., P.G.); University Paris-Saclay/APHP, Hospita
  • Schulthess P; VectivBio AG, Basel, Switzerland (F.B.); Centre for Human Drug Research, Leiden, Netherlands (A.C.K., M.L.d.K., K.R.B., M.v.G., M.Mo., P.G.); LYO-X AG, Basel, Switzerland (P.S., M.Ma.); Leiden University Medical Center, Leiden, Netherlands (A.C.K., M.Mo., P.G.); University Paris-Saclay/APHP, Hospita
  • Machacek M; VectivBio AG, Basel, Switzerland (F.B.); Centre for Human Drug Research, Leiden, Netherlands (A.C.K., M.L.d.K., K.R.B., M.v.G., M.Mo., P.G.); LYO-X AG, Basel, Switzerland (P.S., M.Ma.); Leiden University Medical Center, Leiden, Netherlands (A.C.K., M.Mo., P.G.); University Paris-Saclay/APHP, Hospita
  • de Kam ML; VectivBio AG, Basel, Switzerland (F.B.); Centre for Human Drug Research, Leiden, Netherlands (A.C.K., M.L.d.K., K.R.B., M.v.G., M.Mo., P.G.); LYO-X AG, Basel, Switzerland (P.S., M.Ma.); Leiden University Medical Center, Leiden, Netherlands (A.C.K., M.Mo., P.G.); University Paris-Saclay/APHP, Hospita
  • Bergmann KR; VectivBio AG, Basel, Switzerland (F.B.); Centre for Human Drug Research, Leiden, Netherlands (A.C.K., M.L.d.K., K.R.B., M.v.G., M.Mo., P.G.); LYO-X AG, Basel, Switzerland (P.S., M.Ma.); Leiden University Medical Center, Leiden, Netherlands (A.C.K., M.Mo., P.G.); University Paris-Saclay/APHP, Hospita
  • van Gent M; VectivBio AG, Basel, Switzerland (F.B.); Centre for Human Drug Research, Leiden, Netherlands (A.C.K., M.L.d.K., K.R.B., M.v.G., M.Mo., P.G.); LYO-X AG, Basel, Switzerland (P.S., M.Ma.); Leiden University Medical Center, Leiden, Netherlands (A.C.K., M.Mo., P.G.); University Paris-Saclay/APHP, Hospita
  • Moerland M; VectivBio AG, Basel, Switzerland (F.B.); Centre for Human Drug Research, Leiden, Netherlands (A.C.K., M.L.d.K., K.R.B., M.v.G., M.Mo., P.G.); LYO-X AG, Basel, Switzerland (P.S., M.Ma.); Leiden University Medical Center, Leiden, Netherlands (A.C.K., M.Mo., P.G.); University Paris-Saclay/APHP, Hospita
  • Crenn P; VectivBio AG, Basel, Switzerland (F.B.); Centre for Human Drug Research, Leiden, Netherlands (A.C.K., M.L.d.K., K.R.B., M.v.G., M.Mo., P.G.); LYO-X AG, Basel, Switzerland (P.S., M.Ma.); Leiden University Medical Center, Leiden, Netherlands (A.C.K., M.Mo., P.G.); University Paris-Saclay/APHP, Hospita
  • Greig G; VectivBio AG, Basel, Switzerland (F.B.); Centre for Human Drug Research, Leiden, Netherlands (A.C.K., M.L.d.K., K.R.B., M.v.G., M.Mo., P.G.); LYO-X AG, Basel, Switzerland (P.S., M.Ma.); Leiden University Medical Center, Leiden, Netherlands (A.C.K., M.Mo., P.G.); University Paris-Saclay/APHP, Hospita
  • Gal P; VectivBio AG, Basel, Switzerland (F.B.); Centre for Human Drug Research, Leiden, Netherlands (A.C.K., M.L.d.K., K.R.B., M.v.G., M.Mo., P.G.); LYO-X AG, Basel, Switzerland (P.S., M.Ma.); Leiden University Medical Center, Leiden, Netherlands (A.C.K., M.Mo., P.G.); University Paris-Saclay/APHP, Hospita
J Pharmacol Exp Ther ; 386(2): 129-137, 2023 08.
Article em En | MEDLINE | ID: mdl-37316329

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Citrulina Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Citrulina Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article