CLIC4 Regulates Endothelial Barrier Control by Mediating PAR1 Signaling via RhoA.

Kleinjan, Matthew L; Mao, De Yu; Naiche, L A; Joshi, Jagdish Chandra; Gupta, Ahana; Jesse, Jordan J; Shaye, Daniel D; Mehta, Dolly; Kitajewski, Jan

Kleinjan, Matthew L; Mao, De Yu; Naiche, L A; Joshi, Jagdish Chandra; Gupta, Ahana; Jesse, Jordan J; Shaye, Daniel D; Mehta, Dolly; Kitajewski, Jan.

Afiliação

Kleinjan ML; Department of Physiology and Biophysics (M.L.K., D.Y.M., L.A.N., A.G., J.J.J., D.D.S., J.K.), University of Illinois at Chicago.
Mao Y; Department of Physiology and Biophysics (M.L.K., D.Y.M., L.A.N., A.G., J.J.J., D.D.S., J.K.), University of Illinois at Chicago.
Naiche LA; Department of Physiology and Biophysics (M.L.K., D.Y.M., L.A.N., A.G., J.J.J., D.D.S., J.K.), University of Illinois at Chicago.
Joshi JC; Department of Pharmacology (J.C.J., D.M.), University of Illinois at Chicago.
Gupta A; Department of Physiology and Biophysics (M.L.K., D.Y.M., L.A.N., A.G., J.J.J., D.D.S., J.K.), University of Illinois at Chicago.
Jesse JJ; Department of Physiology and Biophysics (M.L.K., D.Y.M., L.A.N., A.G., J.J.J., D.D.S., J.K.), University of Illinois at Chicago.
Shaye DD; Department of Physiology and Biophysics (M.L.K., D.Y.M., L.A.N., A.G., J.J.J., D.D.S., J.K.), University of Illinois at Chicago.
Mehta D; Department of Pharmacology (J.C.J., D.M.), University of Illinois at Chicago.
Kitajewski J; Department of Physiology and Biophysics (M.L.K., D.Y.M., L.A.N., A.G., J.J.J., D.D.S., J.K.), University of Illinois at Chicago.

Arterioscler Thromb Vasc Biol ; 43(8): 1441-1454, 2023 08.

Article em En | MEDLINE | ID: mdl-37317855

Assuntos

Receptor PAR-1; Proteína rhoA de Ligação ao GTP; Humanos; Camundongos; Animais; Receptor PAR-1/genética; Receptor PAR-1/metabolismo; Proteína rhoA de Ligação ao GTP/metabolismo; Trombina/farmacologia; Trombina/metabolismo; Endotélio/metabolismo; Células Endoteliais da Veia Umbilical Humana/metabolismo; Células Cultivadas; Canais de Cloreto/genética; Canais de Cloreto/metabolismo; Proteínas Mitocondriais/metabolismo

Palavras-chave

RhoA GTP-binding protein; chloride intracellular channel; human umbilical vein endothelial cell; protease-activated receptor 1; thrombin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína rhoA de Ligação ao GTP / Receptor PAR-1 Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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