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A TCF-based fluorescent probe to determine nitroreductase (NTR) activity for a broad-spectrum of bacterial species.
Yan, Kai-Cheng; Gardiner, Jordan E; Sedgwick, Adam C; Thet, Naing; Heylen, Rachel A; James, Tony D; Jenkins, A Toby A; He, Xiao-Peng.
Afiliação
  • Yan KC; Department of Chemistry, University of Bath, Bath, BA2 7AY, UK. t.d.james@bath.ac.uk.
  • Gardiner JE; Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Rd., Sh
  • Sedgwick AC; Department of Chemistry, University of Bath, Bath, BA2 7AY, UK. t.d.james@bath.ac.uk.
  • Thet N; Chemistry Research Laboratory, University of Oxford, Mansfield Road, OX1 3TA, UK.
  • Heylen RA; Department of Chemistry, University of Bath, Bath, BA2 7AY, UK. t.d.james@bath.ac.uk.
  • James TD; Department of Chemistry, University of Bath, Bath, BA2 7AY, UK. t.d.james@bath.ac.uk.
  • Jenkins ATA; Department of Chemistry, University of Bath, Bath, BA2 7AY, UK. t.d.james@bath.ac.uk.
  • He XP; School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 453007, China.
Chem Commun (Camb) ; 59(53): 8278-8281, 2023 Jun 29.
Article em En | MEDLINE | ID: mdl-37318211
A nitroreductase (NTR) responsive fluorescent probe with long wavelength fluorescence emission was used to determine the NTR activity of a selection of bacterial species under a range of different bacterial growth conditions ensuring applicability under multiple complex clinical environments, where sensitivity, reaction time, and the detection accuracy were suitable for planktonic cultures and biofilms.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nitrorredutases / Corantes Fluorescentes Idioma: En Ano de publicação: 2023 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nitrorredutases / Corantes Fluorescentes Idioma: En Ano de publicação: 2023 Tipo de documento: Article