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The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics.
Yee, Sook Wah; Macdonald, Christian; Mitrovic, Darko; Zhou, Xujia; Koleske, Megan L; Yang, Jia; Silva, Dina Buitrago; Grimes, Patrick Rockefeller; Trinidad, Donovan; More, Swati S; Kachuri, Linda; Witte, John S; Delemotte, Lucie; Giacomini, Kathleen M; Coyote-Maestas, Willow.
Afiliação
  • Yee SW; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, United States.
  • Macdonald C; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, United States.
  • Mitrovic D; Science for Life Laboratory, Department of Applied Physics, KTH Royal Institute of Technology, 12121 Solna, Sweden.
  • Zhou X; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, United States.
  • Koleske ML; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, United States.
  • Yang J; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, United States.
  • Silva DB; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, United States.
  • Grimes PR; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, United States.
  • Trinidad D; Department of Medicine, Division of Infectious Disease, University of California, San Francisco, United States.
  • More SS; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, United States.
  • Kachuri L; Current address: Center for Drug Design (CDD), College of Pharmacy, University of Minnesota, Minnesota, United States.
  • Witte JS; Epidemiology and Population Health, Stanford University, California, United States.
  • Delemotte L; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, United States.
  • Giacomini KM; Epidemiology and Population Health, Stanford University, California, United States.
  • Coyote-Maestas W; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, United States.
bioRxiv ; 2023 Jun 07.
Article em En | MEDLINE | ID: mdl-37333090
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article