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Targeting gasdermin E in neurodegenerative diseases.
Zhou, Zhi Dong; Yi, Ling Xiao; Tan, Eng King.
Afiliação
  • Zhou ZD; National Neuroscience Institute of Singapore, 11 Jalan Tan Tock Seng, Singapore, 30843, Singapore; Signature Research Program in Neuroscience and Behavioral Disorders, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore. Electronic address: zhidong.zhou@duke-nus.edu.sg.
  • Yi LX; National Neuroscience Institute of Singapore, 11 Jalan Tan Tock Seng, Singapore, 30843, Singapore.
  • Tan EK; National Neuroscience Institute of Singapore, 11 Jalan Tan Tock Seng, Singapore, 30843, Singapore; Department of Neurology, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore; Signature Research Program in Neuroscience and Behavioral Disorders, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore. Electronic address: tan.eng.king@sgh.com.sg.
Cell Rep Med ; 4(6): 101075, 2023 06 20.
Article em En | MEDLINE | ID: mdl-37343522
Neel et al. identified pathophysiologic clues linking gasdermin-E (GSDME) with frontotemporal dementia and amyotrophic lateral sclerosis.1 Therapeutic studies targeting GSDME may provide a viable approach for neurodegenerative diseases.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Neurodegenerativas / Demência Frontotemporal / Esclerose Lateral Amiotrófica Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Neurodegenerativas / Demência Frontotemporal / Esclerose Lateral Amiotrófica Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article