Inverse association between Mediterranean diet and risk of multiple sclerosis.
Mult Scler
; 29(9): 1118-1125, 2023 08.
Article
em En
| MEDLINE
| ID: mdl-37366345
ABSTRACT
OBJECTIVE:
There is some evidence implicating diet in the development of inflammatory diseases. We aimed to study the influence of dietary habits on the risk of developing multiple sclerosis (MS).METHODS:
We used a population-based case-control study recruiting incident cases of MS (1953 cases, 3557 controls). Subjects with different dietary habits 5 years prior to MS diagnosis were compared regarding MS risk by calculating odds ratios (OR) with 95% confidence intervals (CI) using logistic regression models. Adjustment was made for a large number of environmental and lifestyle habits, including ancestry, smoking, alcohol consumption, body mass index, physical activity, and sun exposure habits.RESULTS:
Mediterranean diet was associated with lower risk of developing MS (adjusted OR = 0.54, 95% CI 0.34-0.86, p = 0.009), compared with Western-style diet. There was no significant association between vegetarian/vegan diet and MS risk (adjusted OR = 0.96, 95% CI 0.75-1.24, p = 0.976), nor between diet with low glycemic index and MS risk (adjusted OR = 0.93, 95% CI 0.60-1.42, p = 0.518).CONCLUSIONS:
Mediterranean diet may exert a protective influence regarding the risk of subsequently developing MS compared with Western-style diet.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dieta Mediterrânea
/
Esclerose Múltipla
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article