Novel Potential Janus Kinase Inhibitors with Therapeutic Prospects in Rheumatoid Arthritis Addressed by In Silico Studies.

Radu, Andrei-Flavius; Bungau, Simona Gabriela; Negru, Andrei Paul; Uivaraseanu, Bogdan; Bogdan, Mihaela Alexandra

Radu, Andrei-Flavius; Bungau, Simona Gabriela; Negru, Andrei Paul; Uivaraseanu, Bogdan; Bogdan, Mihaela Alexandra.

Afiliação

Radu AF; Doctoral School of Biological and Biomedical Sciences, University of Oradea, 410087 Oradea, Romania.
Bungau SG; Department of Preclinical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.
Negru AP; Doctoral School of Biological and Biomedical Sciences, University of Oradea, 410087 Oradea, Romania.
Uivaraseanu B; Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, Romania.
Bogdan MA; Doctoral School of Biological and Biomedical Sciences, University of Oradea, 410087 Oradea, Romania.

Molecules ; 28(12)2023 Jun 12.

Article em En | MEDLINE | ID: mdl-37375255

Assuntos

Artrite Reumatoide; Doenças Autoimunes; Inibidores de Janus Quinases; Humanos; Inibidores de Janus Quinases/farmacologia; Inibidores de Janus Quinases/uso terapêutico; Simulação de Acoplamento Molecular; Artrite Reumatoide/tratamento farmacológico; Doenças Autoimunes/tratamento farmacológico; Inflamação/tratamento farmacológico; Janus Quinase 2; Janus Quinases

Palavras-chave

DMARDs; Janus kinase inhibitors; molecular docking; protein targets; rheumatoid arthritis; virtual screening

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Doenças Autoimunes / Inibidores de Janus Quinases Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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