[Application of a low copper diet guidance based on food exchange portions in children with hepatolenticular degeneration]. / åºäºé£ç©äº¤æ¢ä»½æ³çä½é饮é£æ导å¨èè±ç¶æ ¸åæ§æ£å¿ä¸çåºç¨ææ.
Zhongguo Dang Dai Er Ke Za Zhi
; 25(6): 612-618, 2023 Jun 15.
Article
em Zh
| MEDLINE
| ID: mdl-37382131
ABSTRACT
OBJECTIVES:
To study the efficacy of a low-copper diet guidance based on food exchange portions in children with hepatolenticular degeneration.METHODS:
A self-controlled study was conducted from July 2021 to June 2022, including 30 children under the age of 18 who were diagnosed with hepatolenticular degeneration and poorly controlled with a low-copper diet. During the medical visit, personalized low-copper diet guidance was provided to the children and their parents using a copper-containing food exchange table and a copper food exchange chart. During home care, compliance with the low-copper diet of the children was improved by recording dietary diaries and conducting regular follow-ups. The changes in 24-hour urine copper level, liver function indicators, and the low-copper diet knowledge of the children's parents were observed before and after the intervention, with no change in the original drug treatment.RESULTS:
After 8, 16, and 24 weeks of intervention, the 24-hour urine copper level decreased significantly compared to before intervention (P<0.05). When compared to 8-week intervention, the urine copper level decreased significantly after 16 and 24 weeks of intervention. The 24-hour urine copper level after 24 weeks of intervention decreased significantly compared to 16 weeks of intervention (P<0.05).After 24 weeks of intervention, the alanine aminotransferase and aspartate aminotransferase levels decreased significantly compared to before intervention (P<0.05). Additionally, in 16 of the cases (53%), alanine aminotransferase and aspartate aminotransferase returned to normal levels. Following 8 weeks of intervention, the low-copper diet knowledge of the children's parents increased significantly (P<0.05).CONCLUSIONS:
A low-copper diet guidance based on food exchange portions can effectively decrease the urine copper level and improve liver function in children with hepatolenticular degeneration. Furthermore, it can increase the low-copper diet knowledge of the children's parents.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Degeneração Hepatolenticular
Tipo de estudo:
Guideline
Limite:
Child
/
Humans
Idioma:
Zh
Ano de publicação:
2023
Tipo de documento:
Article