Loss of NOR-1 represses muscle metabolism through mTORC1-mediated signaling and mitochondrial gene expression in C2C12 myotubes.

Paez, Hector G; Ferrandi, Peter J; Pitzer, Christopher R; Mohamed, Junaith S; Alway, Stephen E

Paez, Hector G; Ferrandi, Peter J; Pitzer, Christopher R; Mohamed, Junaith S; Alway, Stephen E.

Afiliação

Paez HG; Department of Physiology, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Ferrandi PJ; Integrated Biomedical Sciences Graduate Program, College of Graduate Health Sciences, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Pitzer CR; Laboratory of Muscle Biology and Sarcopenia, Department of Physical Therapy, College of Health Professions, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Mohamed JS; Division of Regenerative and Rehabilitation Sciences, Center for Muscle, Metabolism and Neuropathology, College of Health Professions, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Alway SE; Integrated Biomedical Sciences Graduate Program, College of Graduate Health Sciences, University of Tennessee Health Science Center, Memphis, Tennessee, USA.

FASEB J ; 37(8): e23050, 2023 08.

Article em En | MEDLINE | ID: mdl-37389860

Assuntos

Diabetes Mellitus Tipo 2; Resistência à Insulina; Humanos; Expressão Gênica; Genes Mitocondriais; Alvo Mecanístico do Complexo 1 de Rapamicina/genética; Fibras Musculares Esqueléticas; Músculo Esquelético; Obesidade/genética

Palavras-chave

inactivity; metabolism; mitochondria; muscle; myoblast; obesity

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Diabetes Mellitus Tipo 2 Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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