In vivo transmission electron microscopy of the alternating structure of the protrusions between adjacent macrophage-like cells on micropatterns.
J Oral Biosci
; 65(3): 259-263, 2023 09.
Article
em En
| MEDLINE
| ID: mdl-37393036
ABSTRACT
OBJECTIVES:
We investigated the behavior of macrophages in the defined microtopography of materials.METHODS:
Patterned cyclo-olefin polymer films were implanted into the femurs of seven-week-old rats. After 1 and 4 weeks, the rats were fixed with glutaraldehyde and OsO4, and their bones were observed with transmission electron microscopy (TEM).RESULTS:
TEM and segmentation revealed an alternating structure in which multiple protrusions of adjacent macrophage-like cells overlapped. They were approximately 2 µm long and almost uniform in width, and were induced by the limited topography.CONCLUSION:
New structures appeared between the macrophage-like cells as a result of microtopography.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Macrófagos
Limite:
Animals
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article