Systemic delivery of specific and efficient CRISPR/Cas9 system targeting HPV16 oncogenes using LL-37 antimicrobial peptide in C57BL/6 mice.

Khairkhah, Niloofar; Bolhassani, Azam; Rajaei, Farzad; Najafipour, Reza

Khairkhah, Niloofar; Bolhassani, Azam; Rajaei, Farzad; Najafipour, Reza.

Afiliação

Khairkhah N; Department of Molecular Medicine, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.
Bolhassani A; Department of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, Iran.
Rajaei F; Cellular and Molecular Research Center, Research Institute for Non-communicable Disease, Qazvin University of Medical Sciences, Qazvin, Iran.
Najafipour R; Department of Molecular Medicine, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.

J Med Virol ; 95(7): e28934, 2023 07.

Article em En | MEDLINE | ID: mdl-37403986

Assuntos

Sistemas CRISPR-Cas; Papillomavirus Humano 16; Camundongos; Animais; Humanos; Papillomavirus Humano 16/genética; Peptídeos Antimicrobianos; Camundongos Endogâmicos C57BL; Oncogenes

Palavras-chave

CRISPR/Cas9; LL-37 antimicrobial peptide; gene editing; human papillomavirus; systemic delivery

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Papillomavirus Humano 16 / Sistemas CRISPR-Cas Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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