Targeting of HBP1/TIMP3 axis as a novel strategy against breast cancer.

Zhou, Yue; Zhang, Tongjia; Wang, Shujie; Yang, Ruixiang; Jiao, Zitao; Lu, Kejia; Li, Hui; Jiang, Wei; Zhang, Xiaowei

Zhou, Yue; Zhang, Tongjia; Wang, Shujie; Yang, Ruixiang; Jiao, Zitao; Lu, Kejia; Li, Hui; Jiang, Wei; Zhang, Xiaowei.

Afiliação

Zhou Y; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing 100191, PR China.
Zhang T; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing 100191, PR China.
Wang S; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing 100191, PR China.
Yang R; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing 100191, PR China.
Jiao Z; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing 100191, PR China.
Lu K; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing 100191, PR China.
Li H; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing 100191, PR China.
Jiang W; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing 100191, PR China.
Zhang X; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing 100191, PR China. Electronic address: xiaoweizhang@bjmu.edu.cn.

Pharmacol Res ; 194: 106846, 2023 08.

Article em En | MEDLINE | ID: mdl-37414199

Assuntos

Neoplasias da Mama; Humanos; Feminino; Neoplasias da Mama/tratamento farmacológico; Neoplasias da Mama/genética; RNA Mensageiro/genética; Prognóstico; Regiões Promotoras Genéticas; Proteínas de Grupo de Alta Mobilidade/genética; Proteínas Repressoras/genética; Proteínas Repressoras/metabolismo; Inibidor Tecidual de Metaloproteinase-3/genética; Inibidor Tecidual de Metaloproteinase-3/metabolismo

Palavras-chave

7,12-Dimethylbenz[a]anthracene (DMBA, PubChem CID: 6001); Breast cancer; Disodium phosphate dodecahydrate (PubChem CID: 61456); Epigallocatechin Gallate (PubChem CID: 65064); Ethylenediaminetetraacetic acid (PubChem CID: 6049); HBP1; MMP2/9; PTEN; Potassium Chloride (PubChem CID:4873); Potassium dihydrogen phosphate (PubChem CID: 516951); Radiotherapy; Sodium Chloride (PubChem CID: 5234); Sodium dodecyl sulfate (PubChem CID: 3423265); TIMP3; Tamoxifen (PubChem CID: 2733526); Tromethamine (PubChem CID: 6503)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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