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Efficacy and safety of the C5 inhibitor crovalimab in complement inhibitor-naive patients with PNH (COMMODORE 3): A multicenter, Phase 3, single-arm study.
Liu, Hui; Xia, Linghui; Weng, Jianyu; Zhang, Fengkui; He, Chuan; Gao, Sujun; Jia, Jinsong; Chang, Alice C; Lundberg, Pontus; Shi, Jane; Sima, Camelia S; Sostelly, Alexandre; Sreckovic, Sasha; Xiao, Zhenyu; Zhang, Zilu; Fu, Rong.
Afiliação
  • Liu H; Department of Hematology, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.
  • Xia L; Division of Bone Marrow Transplantation, Institute of Hematology, Wuhan Union Hospital, Wuhan, People's Republic of China.
  • Weng J; Department of Hematology, Guangdong Provincial People's Hospital, Guangdong, People's Republic of China.
  • Zhang F; Department of Hematology, Institute of Hematology and Blood Diseases Hospital, Tianjin, People's Republic of China.
  • He C; Department of Hematology, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
  • Gao S; Department of Hematology, The First Hospital of Jilin University, Changchun, People's Republic of China.
  • Jia J; Department of Hematology, Peking University People's Hospital, Beijing, People's Republic of China.
  • Chang AC; Product Development Hematology, Genentech, Inc., South San Francisco, California, USA.
  • Lundberg P; Oncology Biomarker Development, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Shi J; Product Development Safety, Roche Product Development, Shanghai, People's Republic of China.
  • Sima CS; PD Oncology and Hematology, Genentech, Inc., South San Francisco, California, USA.
  • Sostelly A; Roche Pharma Research and Early Development, Clinical Pharmacology, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Sreckovic S; Product Development Safety, Genentech, Inc., South San Francisco, California, USA.
  • Xiao Z; Department of Clinical Science, Roche Product Development, Shanghai, People's Republic of China.
  • Zhang Z; Department of Data Sciences, Roche Product Development, Shanghai, People's Republic of China.
  • Fu R; Department of Hematology, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.
Am J Hematol ; 98(9): 1407-1414, 2023 09.
Article em En | MEDLINE | ID: mdl-37421604
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hemoglobinúria Paroxística Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Child / Humans / Middle aged Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hemoglobinúria Paroxística Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Child / Humans / Middle aged Idioma: En Ano de publicação: 2023 Tipo de documento: Article