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First-line atezolizumab monotherapy versus single-agent chemotherapy in patients with non-small-cell lung cancer ineligible for treatment with a platinum-containing regimen (IPSOS): a phase 3, global, multicentre, open-label, randomised controlled study.
Lee, Siow Ming; Schulz, Christian; Prabhash, Kumar; Kowalski, Dariusz; Szczesna, Aleksandra; Han, Baohui; Rittmeyer, Achim; Talbot, Toby; Vicente, David; Califano, Raffaele; Cortinovis, Diego; Le, Anh Tuan; Huang, Dingzhi; Liu, Geoffrey; Cappuzzo, Federico; Reyes Contreras, Jessica; Reck, Martin; Palmero, Ramon; Mak, Milena Perez; Hu, Youyou; Morris, Stefanie; Höglander, Elen; Connors, Mary; Biggane, Alice M; Vollan, Hans Kristian; Peters, Solange.
Afiliação
  • Lee SM; Department of Oncology, University College London Hospitals NHS Foundation Trust, CRUK Lung Cancer Centre of Excellence and UCL Cancer Institute, London, UK. Electronic address: sm.lee@nhs.net.
  • Schulz C; Bereich Pneumologie Klinik und Poliklinik für Innere Medizin II, University Hospital Regensburg, Regensburg, Germany.
  • Prabhash K; Department of Medical Oncology, Tata Memorial Hospital, Mumbai, India.
  • Kowalski D; Department of Lung Cancer and Thoracic Tumors, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
  • Szczesna A; Department of Lung Diseases, Mazowieckie Centrum Leczenia Chorób Pluc i Gruzlicy, Otwock, Poland.
  • Han B; Department of Pulmonary Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
  • Rittmeyer A; Department of Thoracic Oncology, LKI Lungenfachklinik Immenhausen, Immenhausen, Germany.
  • Talbot T; Department of Oncology, Royal Cornwall Hospitals NHS Trust, Truro, UK.
  • Vicente D; Medical Oncology Department, Hospital Universitario Virgen Macarena, Seville, Spain.
  • Califano R; Department of Medical Oncology, The Christie NHS Foundation Trust and Division of Cancer Sciences, University of Manchester, Manchester, UK.
  • Cortinovis D; Department of Medical Oncology, AAST H S Gerardo Monza, Monza, Italy.
  • Le AT; Cho Ray Cancer Centre, Cho Ray Hospital, Ho Chi Minh City, Viet Nam.
  • Huang D; Department of Thoracic Oncology, National Clinical Research Centre for Cancer, Tianjin Medical University Cancer Institute & Hospital, Tianjin, China.
  • Liu G; Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON, Canada.
  • Cappuzzo F; Department of Oncology, National Cancer Institute IRCCS Regina Elena, Rome, Italy.
  • Reyes Contreras J; Oncologico Potosino, San Luis Potosí, Mexico.
  • Reck M; Department of Thoracic Oncology, Lungen Clinic Grosshansdorf, Airway Research Centre North, German Centre for Lung Research, Grosshansdorf, Germany.
  • Palmero R; Department of Medical Oncology, Catalan Institute of Oncology, Hospital Duran i Reynals, L'Hospitalet, Barcelona, Spain.
  • Mak MP; Department of Medical Oncology, Instituto do Cancer do Estado de Sao Paulo, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil.
  • Hu Y; F Hoffmann-La Roche, Basel, Switzerland.
  • Morris S; F Hoffmann-La Roche, Basel, Switzerland.
  • Höglander E; F Hoffmann-La Roche, Basel, Switzerland.
  • Connors M; Genentech, San Francisco, CA, USA.
  • Biggane AM; F Hoffmann-La Roche, Basel, Switzerland; Pfizer, Kent, UK.
  • Vollan HK; F Hoffmann-La Roche, Basel, Switzerland.
  • Peters S; Centre Hospitalier Universitaire Vaudois, Lausanne University, Lausanne, Switzerland.
Lancet ; 402(10400): 451-463, 2023 08 05.
Article em En | MEDLINE | ID: mdl-37423228
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Tipo de estudo: Clinical_trials Limite: Aged / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Tipo de estudo: Clinical_trials Limite: Aged / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article