Genome-Wide Association Study for the Genetic Determinants of Thiopurine Methyltransferase Protein Expression in Human Livers and Racial Differences.

Smith, Logan S; Wang, Xinwen; Shi, Jian; He, Bing; Zhu, Hao-Jie

Smith, Logan S; Wang, Xinwen; Shi, Jian; He, Bing; Zhu, Hao-Jie.

Afiliação

Smith LS; Department of Clinical Pharmacy, University of Michigan, Ann Arbor, MI, 48109, USA.
Wang X; Department of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, OH, 44272, USA.
Shi J; Bristol Myers Squibb, 3401 Princeton Pike, Lawrence Township, NJ, 08648, USA.
He B; Department of Computational Medicine and Bioinformatics, Medical School, University of Michigan, Ann Arbor, MI, USA.
Zhu HJ; Department of Clinical Pharmacy, University of Michigan, Ann Arbor, MI, 48109, USA. hjzhu@med.umich.edu.

Pharm Res ; 40(11): 2525-2531, 2023 Nov.

Article em En | MEDLINE | ID: mdl-37430149

Assuntos

Estudo de Associação Genômica Ampla; Metiltransferases; Humanos; Fatores Raciais; Metiltransferases/genética; Genótipo; Polimorfismo de Nucleotídeo Único; Fígado

Palavras-chave

GWAS; TPMT; pharmacogenomics; proteomics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estudo de Associação Genômica Ampla / Metiltransferases Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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