Embolic stroke in a woman with mitral valve prolapse who used oral contraceptives.
Chest
; 90(3): 454-5, 1986 Sep.
Article
em En
| MEDLINE
| ID: mdl-3743165
ABSTRACT
PIP: A 21-year old women taking oral contraceptives suffered thromboembolic stroke associated with mitral valve prolapse. She had been using an unspecified oral contraceptive for 3 months postpartum, and had smoked a pack a day for 5 years. She complained of sudden right orbital headache, left-sided weakness and pain. Clinical exam showed left sided anopsia, facial paralysis, tongue protrusion, parietal sensory deficit, and loss of position sense. Computed tomography suggested a lesion near the right middle cerebral artery; and cerebral angiography revealed an 8 x 2 mm filling defect in that artery. A midsystolic click without a murmur was evident in the cardiac exam. Thickened, redundant mitral valve leaflets with marked prolapse, and a mass on the atrial side of the posterior leaflet appeared on the echocardiogram. The atrial thrombus was considered the source of the apparent embolism in the cerebral artery. Oral contraceptives have been found to increase the risk of thrombotic stroke and venous thromboembolism. Therefore, women with known mitral valve prolapse or leaflets may be advised not to use the pill.
Palavras-chave
Biology; Cardiovascular Effects; Case Studies; Central Nervous System; Central Nervous System Effects; Cerebrovascular Effects; Contraception; Contraceptive Methods--contraindications; Contraceptive Methods--side effects; Diseases; Embolism; Family Planning; Heart Diseases; Neurologic Effects; Oral Contraceptives--contraindications; Oral Contraceptives--side effects; Physiology; Postpartum Women; Research Methodology; Smoking; Studies; Thromboembolism; Vascular Diseases
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Embolia e Trombose Intracraniana
/
Prolapso da Valva Mitral
/
Anticoncepcionais Orais
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Ano de publicação:
1986
Tipo de documento:
Article