Th1-like Treg cells are dressed to suppress anti-tumor immunity.

Ramirez, Delaney E; Turk, Mary Jo

Ramirez, Delaney E; Turk, Mary Jo.

Afiliação

Ramirez DE; Dartmouth Cancer Center and the Geisel School of Medicine at Dartmouth, Department of Microbiology and Immunology, Lebanon, NH, USA.
Turk MJ; Dartmouth Cancer Center and the Geisel School of Medicine at Dartmouth, Department of Microbiology and Immunology, Lebanon, NH, USA. Electronic address: mary.jo.turk@dartmouth.edu.

Immunity ; 56(7): 1437-1439, 2023 07 11.

Article em En | MEDLINE | ID: mdl-37437535

RESUMO

Mechanisms of Th1-like Treg suppression are unknown in cancer. Two studies in Immunity by Ayala et al. and Zagorulya et al. demonstrate that Th1-like Treg cells interact with type 1 dendritic cells in tumors and draining lymph nodes to potently suppress anti-tumor immunity.

Assuntos

Células Dendríticas; Neoplasias; Linfócitos T Reguladores; Linfócitos T Reguladores/imunologia; Neoplasias/imunologia; Células Dendríticas/imunologia; Linfonodos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Dendríticas / Linfócitos T Reguladores / Neoplasias Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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