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Cardiac magnetic resonance predictors for successful primary biventricular repair of unbalanced complete common atrioventricular canal.
Jones, Andrea L; White, Brian R; Ghosh, Reena M; Mondal, Antara; Ampah, Steve; Ho, Deborah Y; Whitehead, Kevin; Harris, Matthew A; Biko, David M; Partington, Sara; Fuller, Stephanie; Cohen, Meryl S; Fogel, Mark A.
Afiliação
  • Jones AL; Division of Pediatric Cardiology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • White BR; Division of Pediatric Cardiology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Ghosh RM; Division of Pediatric Cardiology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Mondal A; Department of Biomedical & Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Ampah S; Department of Biomedical & Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Ho DY; Division of Pediatric Cardiology, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA, USA.
  • Whitehead K; Division of Pediatric Cardiology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Harris MA; Division of Pediatric Cardiology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Biko DM; Department of Radiology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Partington S; Division of Pediatric Cardiology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Fuller S; Division of Cardiothoracic Surgery, The Children's Hospital of Philadelphia and the University of Pennsylvania, Philadelphia, PA, USA.
  • Cohen MS; Division of Pediatric Cardiology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Fogel MA; Division of Pediatric Cardiology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Cardiol Young ; 34(2): 387-394, 2024 Feb.
Article em En | MEDLINE | ID: mdl-37462049
ABSTRACT

BACKGROUND:

Patients with unbalanced common atrioventricular canal can be difficult to manage. Surgical planning often depends on pre-operative echocardiographic measurements. We aimed to determine the added utility of cardiac MRI in predicting successful biventricular repair in common atrioventricular canal.

METHODS:

We conducted a retrospective cohort study of children with common atrioventricular canal who underwent MRI prior to repair. Associations between MRI and echocardiographic measures and surgical outcome were tested using logistic regression, and models were compared using area under the receiver operator characteristic curve.

RESULTS:

We included 28 patients (median age at MRI 5.2 months). The optimal MRI model included the novel end-diastolic volume index (using the ratio of left ventricular end-diastolic volume to total end-diastolic volume) and the left ventricle-right ventricle angle in diastole (area under the curve 0.83, p = 0.041). End-diastolic volume index ≤ 0.18 and left ventricle-right ventricle angle in diastole ≤ 72° yield a sensitivity of 83% and specificity of 81% for successful biventricular repair. The optimal multimodality model included the end-diastolic volume index and the echocardiographic atrioventricular valve index with an area under the curve of 0.87 (p = 0.026).

CONCLUSIONS:

Cardiac MRI can successfully predict successful biventricular repair in patients with unbalanced common atrioventricular canal utilising the end-diastolic volume index alone or in combination with the MRI left ventricle-right ventricle angle in diastole or the echocardiographic atrioventricular valve index. A prospective cardiac MRI study is warranted to better define the multimodality characteristic predictive of successful biventricular surgery.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Defeitos dos Septos Cardíacos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Humans / Infant Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Defeitos dos Septos Cardíacos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Humans / Infant Idioma: En Ano de publicação: 2024 Tipo de documento: Article