The Association of Adverse Childhood Experiences with Long-term Mood and Anxiety Disorders After Childhood Traumatic Brain Injury: A Population-based Case-Control Study.
Arch Phys Med Rehabil
; 104(12): 2075-2083, 2023 12.
Article
em En
| MEDLINE
| ID: mdl-37467935
ABSTRACT
OBJECTIVE:
To assess the association between ACEs and the development of psychiatric disorders by age 25 among individuals who sustained TBI prior to age 10.DESIGN:
Population-based case-control study.SETTING:
Olmsted County, Minnesota.PARTICIPANTS:
566 individuals (N=566) who sustained a TBI prior to age 10 were identified and classified using a validated TBI classification system. Among these individuals, cases with a subsequent mood or anxiety disorder prior to age 25 were identified through clinical diagnostic codes and manual record review. For each case, a 11 matched control was randomly selected from individuals with a pediatric TBI who did not have a mood/anxiety disorder prior to the matched case's mood/anxiety disorder.INTERVENTIONS:
Not applicable MAIN OUTCOMEMEASURES:
Development of a mood/anxiety disorder.RESULTS:
Among the 114 matched pairs of individuals with a TBI prior to age 10, a subsequent mood/anxiety diagnosis was significantly associated with a history of 10 of 14 ACE categories and with having an ACE score ≥1 (odds ratio 5.17; 95% confidence interval 2.78-9.59).CONCLUSIONS:
This is the first population-based study to the authors' knowledge showing that among children who sustained a TBI prior to age 10, those who experienced ACEs are at increased risk of developing a mood or anxiety disorder.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Lesões Encefálicas Traumáticas
/
Experiências Adversas da Infância
Tipo de estudo:
Guideline
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Child
/
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article