Regulation of NLRP3 Inflammasome Activation and Inflammatory Exosome Release in Podocytes by Acid Sphingomyelinase During Obesity.

Huang, Dandan; Kidd, Jason M; Zou, Yao; Wu, Xiaoyuan; Gehr, Todd W B; Li, Pin-Lan; Li, Guangbi

Huang, Dandan; Kidd, Jason M; Zou, Yao; Wu, Xiaoyuan; Gehr, Todd W B; Li, Pin-Lan; Li, Guangbi.

Afiliação

Huang D; Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA.
Kidd JM; Division of Nephrology, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA.
Zou Y; Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA.
Wu X; Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA.
Gehr TWB; Division of Nephrology, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA.
Li PL; Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA.
Li G; Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA. guangbi.li@vcuhealth.org.

Inflammation ; 46(5): 2037-2054, 2023 Oct.

Article em En | MEDLINE | ID: mdl-37477734

Assuntos

Exossomos; Podócitos; Animais; Camundongos; Ceramidas/metabolismo; Exossomos/metabolismo; Inflamassomos/metabolismo; Inflamação/metabolismo; Nicotinamida Fosforribosiltransferase/metabolismo; Proteína 3 que Contém Domínio de Pirina da Família NLR/metabolismo; Obesidade/metabolismo; Podócitos/metabolismo; Esfingomielina Fosfodiesterase

Palavras-chave

NLRP3 inflammasome; exosome.; obesity-related glomerulopathy; podocyte

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Podócitos / Exossomos Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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