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Intraperitoneal transplant of Hepatocytes co-Encapsulated with mesenchymal stromal cells in modified alginate microbeads for the treatment of acute Liver failure in Pediatric patients (HELP)-An open-label, single-arm Simon's two stage phase 1 study protocol.
Fitzpatrick, Emer; Filippi, Celine; Jagadisan, Barath; Shivapatham, Dharshene; Anand, Hanish; Lyne, Mike; Stroud, Katherine-Daisy; Newton, Rebecca; DeLord, Marc; Douiri, Abdel; Dhawan, Anil.
Afiliação
  • Fitzpatrick E; Pediatric Liver GI and Nutrition Centre and Mowat Labs, King's College Hospital, London, United Kingdom.
  • Filippi C; King's College London, London, United Kingdom.
  • Jagadisan B; Pediatric Liver GI and Nutrition Centre and Mowat Labs, King's College Hospital, London, United Kingdom.
  • Shivapatham D; King's College London, London, United Kingdom.
  • Anand H; Pediatric Liver GI and Nutrition Centre and Mowat Labs, King's College Hospital, London, United Kingdom.
  • Lyne M; King's College London, London, United Kingdom.
  • Stroud KD; Biomedical Research Centre, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom.
  • Newton R; Pediatric Liver GI and Nutrition Centre and Mowat Labs, King's College Hospital, London, United Kingdom.
  • DeLord M; Biomedical Research Centre, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom.
  • Douiri A; Pediatric Liver GI and Nutrition Centre and Mowat Labs, King's College Hospital, London, United Kingdom.
  • Dhawan A; King's Health Partners Clinical Trials Office, London, United Kingdom.
PLoS One ; 18(7): e0288185, 2023.
Article em En | MEDLINE | ID: mdl-37490429
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Fígado / Falência Hepática Aguda / Células-Tronco Mesenquimais Tipo de estudo: Clinical_trials / Guideline Limite: Child / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Fígado / Falência Hepática Aguda / Células-Tronco Mesenquimais Tipo de estudo: Clinical_trials / Guideline Limite: Child / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article